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Table 2 Genotype and allele frequencies of IL1RA VNTR polymorphism in Thai malaria patients.

From: A functional polymorphism in the IL1B gene promoter, IL1B -31C>T, is not associated with cerebral malaria in Thailand

 

Mild malaria (n = 203)

Cerebral malaria (n = 109)

Association P-valuea

Genotype

   

2/2b

2 (0.010)

2 (0.018)

0.88

2/4

42 (0.207)

24 (0.220)

 

3/4

3 (0.015)

1 (0.009)

 

4/4

154 (0.759)

82 (0.752)

 

4/5

2 (0.010)

0 (0.000)

 

Allele

   

IL1RA

   

2

46 (0.113)

28 (0.128)

0.84

3

3 (0.007)

1 (0.005)

 

4

355 (0.874)

189 (0.867)

 

5

2 (0.005)

0 (0.000)

 
  1. Frequencies are in parentheses.
  2. a P-values were calculated by the Fisher's exact test based on 5 × 2 and 4 × 2 contingency tables for genotype and allele frequency, respectively.
  3. bIt should be noted here that allele with n repeats of VNTR is designated as "n" in this table.
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Malaria Journal

ISSN: 1475-2875

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