Table 1 Baseline characteristics by study group
Characteristic | CQ (N = 45) | CQ-MB (N = 181) | Total (N = 226) |
|---|---|---|---|
Sex | |||
- male | 36(80.0%) | 145(80.1%) | 181(80.1%) |
- female | 9(20.0%) | 36(19.9%) | 45(19.9%) |
Age [months] | |||
- Mean ± SD | 30.0 ± 13.1 | 29.5 ± 14.9 | 29.6 ± 14.5 |
- Median | 28.0 | 27.0 | 27.5 |
Weight [kg] | |||
- Mean ± SD | 10.5 ± 2.8 | 10.6 ± 2.8 | 10.6 ± 2.8 |
- Median | 10.0 | 10.0 | 10.0 |
G6PD deficiency (NFP-test) | |||
- No | 39 (86.7%) | 157 (86.7%) | 196 (86.7%) |
- Yes | 6 (13.3%) | 24 (13.3%) | 30 (13.3%) |
pfcrt gene | |||
- wildtype | 11 (24.4%) | 40 (22.6%) | 51 (23.0%) |
- K76T mutant | 34 (75.6%) | 137 (77.4%) | 171 (77.0%) |
- Missing data | 0 | 4 | 4 |
Haemoglobin [g/dl] | |||
- Mean ± SD | 10.3 ± 1.3 | 10.4 ± 1.4 | 10.4 ± 1.4 |
- Median | 10.2 | 10.2 | 10.2 |
Haematocrit [%] | |||
- Mean ± SD | 27.9 ± 2.6 | 29.4 ± 3.3 | 29.1 ± 3.2 |
- Median | 28.0 | 30.0 | 28.0 |
Creatinine [μmol/l] | |||
- Mean ± SD | 75.3 ± 15.2 | 77.2 ± 14.5 | 76.8 ± 14.6 |
- Median | 74.4 | 76.4 | 75.3 |
P. falciparum parasites/μl log10 values | |||
- Mean ± SD | 4.28 ± 0.54 | 4.35 ± 0.54 | 4.33 ± 0.54 |
- Median | 4.32 | 4.38 | 4.36 |
- Min, Max | 3.40, 5.29 | 3.08, 5.71 | 3.08, 5.71 |