Age-specific IgG subclass responses to recombinant R0-GLURP in Mgome (high transmission village). Panels A, B, C and D represent IgG1, IgG2, IgG3, and IgG4 subclasses, respectively. The levels are presented as arbitrary units on a logarithmic scale. Box plots illustrate medians with 25th, 75th and whiskers for 10th and 90th percentiles including outliers for each IgG subclass. Lines with filled triangles represent prevalence of responders in percentages.