Cytophilic antibodies to Plasmodium falciparum Glutamate Rich Protein are associated with malaria protection in an area of holoendemic transmission

Table 1 Relationship between P. falciparum density (parasites/μl) and anti R0-GLURP IgG levels (log arbitrary unit/ml) at enrolment.

R0-GLURP antibodies	Unadjusted coefficients (95% CI)¹	P-value	Adjusted coefficients (95% CI)²	P-value
IgG	-773 (-805, 689)	0.378	-146 (-533, 3457)	0.15
IgG1	-2136 (-3477, -795)	0.002	-1401 (-2571, -231)	0.019
IgG2	-1512 (-2894, -128)	0.032	-719 (-2135, 697)	0.318
IgG3	-1482(-2542, -423)	0.006	-983 (-1841, -126)	0.025
IgG4	58 (-590, 706)	0.86	195 (-436, 826)	0.542

¹ Univariate linear regression. ² Multiple linear regressions adjusting for the effect of age including age as square root of age. Models using other forms of age correction (age, age × age, log age) gave similar results.

ISSN: 1475-2875