Table 4 Conditional logistic regression to compare genotype combinations to the non-African genotype Sl1/1 McCa/a.
From: Complement receptor 1 polymorphisms associated with resistance to severe malaria in Kenya
| Â | Severe Anaemia | Cerebral Malaria | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Genotype | No. of cases (%) | No. of controls (%) | OR | 95% CI | P | No. of cases (%) | No. of controls (%) | OR | 95% CI | P |
Sl1/1 McCa/a | 11(8) | 10(7) | Ref | - | - | 17(18) | 10(11) | Ref | - | - |
Sl1/2 McCa/a | 33(24) | 34(25) | 0.93 | 0.20 to 4.37 | 0.93 | 23(25) | 25(27) | 0.40 | 0.09 to 1.77 | 0.23 |
Sl2/2 McCa/a | 17(12) | 17(12) | 0.86 | 0.17 to 4.43 | 0.86 | 11(12) | 14(15) | 0.24 | 0.05 to 1.19 | 0.08 |
Sl2/2 McCa/b | 35(26) | 43(31) | 0.53 | 0.12 to 2.34 | 0.40 | 16(17) | 25(27) | 0.18 | 0.04 to 0.77 | 0.02 |
Sl1/2 McCa/b | 30(22) | 23(17) | 1.19 | 0.26 to 5.40 | 0.82 | 21(23) | 15(16) | 0.93 | 0.19 to 4.60 | 0.93 |
Sl2/2 McCb/b | 11(8) | 10(7) | 0.87 | 0.15 to 5.14 | 0.88 | 5(5) | 4(4) | 0.65 | 0.07 to 6.07 | 0.71 |