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Table 1 Population description

From: Lactate levels in severe malarial anaemia are associated with haemozoin-containing neutrophils and low levels of IL-12

   Lactate < 5 mM (N = 14) Lactate > 5 mM (N = 12)
Age (yrs) Median (IQR) 2.68 (1.25–4.87) 1.46 (0.9–3.0)
Male/female ratio 0.75 0.71
Transfused (%) 35.7 50
Impaired consciousness (BCS ≤ 2) (%) 0 25
Respiratory distress (%) 0 25
Parasite density (/μL)* Median (IQR) 1,625 (170–25,527) 163,200 (61,800–242,655)
WAZ (Z-score) Median (IQR) -2.01 (-3.6 to -4.87) -2.54 (-3.5 to -1.31)
Lactate (mM) Median (IQR) 2.3 (1.8–3.2) 6.8 (6.4–9.15)
Haemoglobin (g/dL) Median (IQR) 4.05 (3.7–4.6) 3.8 (3.5–4.3)
MCV (fL) Mean (95%CI) 68.3 (58.1–76.8) 73.6 (65.8–79.3)
HCN (No/500 PMN)* Median (IQR) 6 (3–9) 16 (10–19)
HCM (No/500 MNC) Median (IQR) 25 (11–84) 69 (28.5–84.8)
TNF-α (pg/mL) Median (IQR) 12.4 (7.8–21.0) 27.5 (15.2–40.6)
IL-10 (pg/mL)* Median (IQR) 39.2 (22.4–52.3) 116.7 (68.3–231.5)
IFN-γ (pg/mL) Median (IQR) 2.19 (1.5–3.1) 3.0 (2.4–4.2)
IL-12 (pg/mL)* Median (IQR) 233.15 (198.1–278.3) 130.4 (87.5–184.8)
  1. The clinical characteristics of 26 children studied. The interquartile range (IQR) or the 95% confidence intervals are given. * P < 0.05 (Mann-Whitney test)