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Table 1 Baseline characteristics of study participants, Kindamba, ROC 2004

From: Efficacy of three artemisinin combination therapies for the treatmentof uncomplicated Plasmodium falciparum malaria in the Republic of Congo

 

AS + AQ

AS + SP

Coartem

Total

P-value

Number of patients

(% of total)

101 (33.9)

91 (30.5)

106 (35.6)

298

 

Sex: F/M (% F)

46/55 (45.5)

38/53 (41.8)

50/56 (47.2)

134/164 (45.0)

P = 0.74

Age* (months)

20.5 ± 10.7 (7–48)

23.0 ± 11.9 (6–54)

36.1 ± 11.1 (12–59)

26.8 ± 13.2 (12–59)

P < 0.00

1

Weight*(Kg)

9.7 ± 2.3 (6–16)

10.1 ± 2.4 (5–19)

12.7 ± 2.0 (10–20)

10.9 ± 2.6 (5–20)

P < 0.00

1

MUAC* (mm)

142.5 ± 13.8 (112–180)

143.5 ± 11.8 (100–188)

151.5 ± 10.6 (130–190)

146.1 ± 12.7 (100–190)

P < 0.00

1

Haemoglobin*

(g/dl)

8.8 ± 1.7 (5.0–12.8)

9.1 ± 1.7 (5.1–12.3)

9.6 ± 1.7 (5.1–14.2)

9.2 ± 1.7 (5.0–14.2)

P = 0.00

3

Moderate anaemia

(Hgb 5 < 8 g/dl)

30 (29.7)

25 (27.5)

16 (15.2)

71 (23.9)

P = 0.03

Mild anaemia

(Hgb 8 < 11 g/dl)

59 (58.4)

53 (58.2)

66 (62.9)

178 (59.9)

P = 0.80

Temperature *(°C)

38.0 ± 1.2 (35.8–40.0)

37.8 ± 1.3 (34.8–40.7)

37.9 ± 1.3 (34.8–40.7)

37.9 ± 1.3 (34.8–40.7)

P = 0.32

0

Parasite density**

(per μl)

28,941 (2040–200,000)

24,997 (1200–200,000)

23,997 (2000–200,000)

25,890 (1200–200,000)

P = 0.65

1

Gametocytes

23 (22.8)

24 (26.4)

9 (8.5)

56 (18.8)

P = 0.00

3

  1. * Values given as mean ± SD (Standard Deviation) and range (min-max value),
  2. ** Parasite density given as geometric mean and range.
  3. ‡ Anaemia/gametocytemia described by number + proportion of cases with anaemia/gametocytes.