Table 2 Guidelines for grading severity of adverse events
From: Pharmacovigilance of antimalarial treatment in Africa: is it possible?
Grade | Severity | Description |
|---|---|---|
1 | Mild | Awareness of sign or symptom, but easily tolerated: Transient or mild discomfort; no limitation in activity; no medical intervention/therapy required |
2 | Moderate | Discomfort enough to cause interference with usual activity: some assistance may be needed; no or minimal medical intervention required |
3 | Severe | Incapacitating with inability to work or perform usual activity: some assistance usually required; hospitalization possible |
4 | Life-threatening | Extreme limitation in activity, significant assistance required; significant medical intervention/therapy required; hospitalization probable |