Skip to main content

Table 1 Prevalence of mutations conferring resistance to chloroquine and sulfadoxine-pyrimthamine in Plasmodium falciparum isolates from southern Ethiopia (n = 69)

From: High prevalence of drug-resistance mutations in Plasmodium falciparum and Plasmodium vivax in southern Ethiopia

Gene locus

Mutation (%)

Mixed type (%)a

Pfcrt 76

69 (100%)

0 (%)

Pfmdr1 86

45 (65%)

11 (16%)

Dhfr 51

67 (97%)

0 (%)

Dhfr 108

69 (100%)

0 (%)

Dhfr 59

62 (90%)

0 (%)

Dhps 436

0 (0%)

0 (%)

Dhps 437

67 (97%)

0 (%)

Dhps 540

67 (97%)

0 (%)

Dhps 581

0 (0%)

0 (%)

Dhps 613

0 (0%)

0 (%)

Grouped dhfr/dhps alleles

Dhfr I51+N108

7 (10%)

0 (%)

Dhfr R59+N108

2 (3%)

0 (%)

Dhfr triple (I51+R59+N108)

60 (87%)

0 (%)

Dhfr/dhps quadruple (dhfr triple + dhps G437)

0 (0%)

0 (%)

Dhfr/dhps quintuple (quadruple + dhps E540)

59 (86%)

0 (%)

  1. a both wildtype and mutant allele were found