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Table 1 Prevalence of mutations conferring resistance to chloroquine and sulfadoxine-pyrimthamine in Plasmodium falciparum isolates from southern Ethiopia (n = 69)

From: High prevalence of drug-resistance mutations in Plasmodium falciparum and Plasmodium vivax in southern Ethiopia

Gene locus Mutation (%) Mixed type (%)a
Pfcrt 76 69 (100%) 0 (%)
Pfmdr1 86 45 (65%) 11 (16%)
Dhfr 51 67 (97%) 0 (%)
Dhfr 108 69 (100%) 0 (%)
Dhfr 59 62 (90%) 0 (%)
Dhps 436 0 (0%) 0 (%)
Dhps 437 67 (97%) 0 (%)
Dhps 540 67 (97%) 0 (%)
Dhps 581 0 (0%) 0 (%)
Dhps 613 0 (0%) 0 (%)
Grouped dhfr/dhps alleles
Dhfr I51+N108 7 (10%) 0 (%)
Dhfr R59+N108 2 (3%) 0 (%)
Dhfr triple (I51+R59+N108) 60 (87%) 0 (%)
Dhfr/dhps quadruple (dhfr triple + dhps G437) 0 (0%) 0 (%)
Dhfr/dhps quintuple (quadruple + dhps E540) 59 (86%) 0 (%)
  1. a both wildtype and mutant allele were found
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