Limited polymorphism in Plasmodium falciparum ookinete surface antigen, von Willebrand factor A domain-related protein from clinical isolates

Richards, Jack S; MacDonald, Nicholas J; Eisen, Damon P

doi:10.1186/1475-2875-5-55

Table 2 Details of PfWARP and Pfs28 polymorphisms and geographic origin for each isolate

From: Limited polymorphism in Plasmodium falciparum ookinete surface antigen, von Willebrand factor A domain-related protein from clinical isolates

Isolate number	Geographic origin^a	PfsWARP sequence^b			Pfs28 sequence^c
Isolate number	Geographic origin^a	Nucleotide sequence 1221576–1221581	Nucleotide sequence 1221645–1221650	Nucleotide sequence 1221885–1221890	Nucleotide sequence 270–275
3D7	Netherlands	GTCT TT	GTAG TC	CAAA CA	TTTAA A
FC27	Papua New Guinea	GTCC TT	GTAT TC	CAAG CA	X^d
FCR3	Central/South America	GTCC TT	GTAT TC	CAAG CA	X^d
1	Uganda	GTCT TT	GTAC TC	CAAA CA	TTTAA A
2	Papua New Guinea	GTCC TT	GTAT TC	CAAG CA	TTTAG A
3	Papua New Guinea	GTCC TT	GTAT TC	CAAG CA	TTTAG A
4	Ivory Coast	GTCT TT	GTAT TG	CAAA CA	X^d
5	Papua New Guinea	GTCC TT	GTAT TC	CAAG CA	TTTAG A
6	Papua New Guinea	GTCC TT	GTAT TC	CAAG CA	X^d
7	Tanzania	GTCC TT	GTAT TC	CAAG CA	TTTAG A
8	Tanzania	GTCC TT	GTAT TC	CAAG CA	TTTAA A
9	Papua New Guinea	GTCC TT	GTAT TC	CAAG CA	X^d
10	Solomon Islands	GTCC TT	GTAT TC	CAAG CA	TTTAG A
11	Ghana	GTCT TT	GTAT TG	CAAA CA	TTTAA A
12	Papua New Guinea	GTCC TT	GTAT TC	CAAG CA	TTTAG A
13	Papua New Guinea	GTCT TT	GTAG TC	CAAA CA	TTTAG A
14	Papua New Guinea	GTCT TT	GTAT TG	CAAG CA	TTTAA A
15	Pakistan	GTCC TT	GTAT TC	CAAG CA	TTTAG A
16	Papua New Guinea	GTCC TT	GTAT TC	CAAG CA	TTTAG A
17	Papua New Guinea	GTCC TT	GTAT TC	CAAG CA	TTTAG A
18	Kenya	GTCT TT	GTAG TC	CAAA CA	TTTAA A
19	Papua New Guinea	GTCC TT	GTAT TC	CAAG CA	TTTAA A
20	Papua New Guinea	X^d	X^d	X^d	TTTAG A
21	Togo	X^d	X^d	X^d	TTTAA A
22	Papua New Guinea	X^d	X^d	X^d	TTTAA A
23	Tanzania	X^d	X^d	X^d	TTTAA A
24	Zimbabwe	X^d	X^d	X^d	TTTAA A
25	Ghana	X^d	X^d	X^d	TTTAA A
CAMP^e	SE Asia	X^d	X^d	X^d	TTTAA A
LE5^e	Africa	X^d	X^d	X^d	TTTAA A
LF4^e	Africa	X^d	X^d	X^d	TTTAA A
HB3^e	Central/South America	X^d	X^d	X^d	TTTAA A
7G8^e	Central/South America	X^d	X^d	X^d	TTTAA A
Dd2^e	SE Asia	X^d	X^d	X^d	TTTAG A
2D11^e	SE Asia	X^d	X^d	X^d	TTTAG A
2 Philippine isolates^e	SE Asia	X^d	X^d	X^d	TTTAA A
30 Philippine isolates^e	SE Asia	X^d	X^d	X^d	TTTAG A

^a The precise geographic origin of laboratory parasite strains is unclear in some instances
^b Variable nucleotide positions for PfWARP are indicated in bold (GenBank: NC_004329 Region: 1221207...1222079).
^c Variable nucleotide positions for Pfs28 are indicated in bold (GenBank: L25843).
^d The symbol "X" is used to indicate that the isolate was not tested.
^e Theses isolates, laboratory strains and their geographic origin are cited as given in the paper by Hafalla et al [12].

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ISSN: 1475-2875

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