Malaria Journal

Table 5 Log-rank test of probability of survival (i.e. remaining re-infection free), by age group and day 7 lumefantrine concentration.

From: Supervised versus unsupervised antimalarial treatment with six-dose artemether-lumefantrine: pharmacokinetic and dosage-related findings from a clinical trial in Uganda

C [lum]_day7 (ng/mL)	< 5 years			5–14 years			≥15 years			Total
	n_c	n_r	p_surv	n_c	n_r	p_surv	n_c	n_r	p_surv	n_c	n_r	p_surv
<200	47	5	0.889	32	4	0.871	33	2	0.938	112	11	0.898
200–399	51	3	0.940	77	2	0.987	63	2	0.968	191	7	0.968
400–599	20	0	1.000	34	0	1.000	33	0	1.000	87	0	1.000
≥600	11	0	1.000	30	0	1.000	21	0	1.000	62	0	1.000
p-value (trend):	0.002			0.283			0.399			<0.001

n_c = number in category n_r = number of re-infections p_surv = probability of survival

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ISSN: 1475-2875

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