Population dynamics of sporogony for Plasmodium vivax parasites from western Thailand developing within three species of colonized Anopheles mosquitoes

Table 3 Cohort life tables for Plasmodium vivax developing within Anopheles mosquitoes. Stage-specific densities and mortality coefficients (k-values) for each cohort are given, where:k-1 = log₁₀(macrogametocyte) - log₁₀(round stage);k-2 = log₁₀(round stage) - log₁₀(ookinete);k-3 = log₁₀(ookinete) - log₁₀(oocyst);K =k-1 +k-2 +k-3. Values in parentheses = antilogs of averaged k-values. For each Anopheles species, parasite values are ranked in descending order of macrogametocyte densities within the HIGH and LOW categories of infection intensity.

Vol.	Class	Macrogametocyte	k-1	Round stage	k-2	Ookinete	k-3	Oocyst	K
	Anopheles dirus
11	HIGH	2978.0	*	3.23	1.96	32.69	1.40	1.30	3.36
15		1242.0	1.63	29.27	0.00	31.37	0.00	59.50	1.63
2		812.9	1.12	61.05	0.21	37.69	0.35	17.00	1.68
5		416.3	*	42.39	0.33	192.58	0.65	42.70	0.98
6		358.6	1.38	15.08	0.17	10.15	0.63	2.40	2.18
1		332.8	1.44	12.20	0.00	13.43	0.00	25.10	1.44
13		277.7	0.85	39.33	0.52	11.88	0.77	2.00	2.14
3		233.3	1.37	10.02	0.00	14.03	0.00	85.80	1.37
14		96.1	*	6.71	0.77	16.20	0.00	61.70	0.77
12		56.6	1.20	3.54	0.08	2.96	0.00	10.60	1.28
8	LOW	804.4	2.15	5.70	0.77	0.15	0.06	0.00	2.98
7		165.5	0.93	19.63	1.17	1.32	0.25	0.30	2.35
10		138.8	2.06	0.23	0.09	0.00	0.00	0.10	2.15
4		101.8	1.58	2.70	0.34	1.23	0.14	0.60	2.06
9		34.7	1.54	0.00	0.00	0.00	0.00	0.00	1.54
Average Losses		1.44 (27-fold)		0.43 (3-fold)		0.28 (2-fold)		1.86 (72-fold)
	Anopheles minimus
15	HIGH	485.9	1.57	12.96	0.18	8.57	0.00	10.7	1.75
2		318.0	0.97	33.91	0.34	15.48	ND	ND†	ND
13		108.6	0.43	40.54	0.67	8.66	1.34	0.4	2.44
14		37.6	0.67	8.06	0.00	11.17	0.40	4.4	1.07
12		22.2	0.83	3.32	0.52	1.00	0.19	0.3	1.54
8	LOW	314.7	1.60	7.89	0.70	0.76	0.25	0	2.55
7		64.8	0.35	29.18	0.83	4.32	0.64	0	1.82
10		54.3	1.73	0.00	0.00	0.00	ND	ND	ND
9		13.6	1.03	0.37	0.14	0.00	0.00	0	1.17
Average Losses		1.02 (10 -fold)		0.33 (2-fold)		0.40 (2-fold)		1.76 (58-fold)
	Anopheles sawadwongporni
15	HIGH	518.3	1.51	15.92	0.34	7.26	0.58	1.9	2.43
2		339.2	1.00	34.23	0.54	9.98	ND	ND	ND
13		115.9	1.35	5.13	0.56	1.42	ND	ND	ND
3		97.4	1.08	8.08	0.24	4.67	ND	ND	ND
14		40.1	0.67	8.61	0.04	7.82	1.05	0.7	1.76
12		23.6	1.15	0.76	0.18	0.15	0.06	0	1.39
8	LOW	335.7	2.48	0.12	0.05	0.00	ND -	ND	ND
Average Losses		1.27 (19-fold)		0.38 (2-fold)		0.35 (2-fold)		1.83 (68-fold)

* Not calculated because round stages were obviously under-sampled (note corresponding ookinete densities). Corresponding k-2 mortalities were therefore calculated as log₁₀(macrogametocyte) – log₁₀ (ookinete).
† ND = not determined due to insufficient numbers of mosquitoes available.

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