Evaluation of the acquired immune responses to Plasmodium vivax VIR variant antigens in individuals living in malaria-endemic areas of Brazil

Table 2 Frequency of malaria exposed individuals with antibodies of distinct IgG subclass specific for recombinant proteins VIR

The percentage of responders was calculated as described in the Methods section. The ELISA was performed using subclass-specific, anti-human IgG1, IgG2, IgG3 or IgG4 and serum samples at a dilution of 1:25. Only serum samples that had total IgG specific for proteins VIR were tested in this assay. The cut-off values were defined as the mean plus 3 standard deviation values obtained from 20 uninfected control sera.

ISSN: 1475-2875