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Table 1 Some changes common to systemic inflammatory states in general, including sepsis and falciparum malaria

From: Human malarial disease: a consequence of inflammatory cytokine release

TNF, IL-1, iNOS and IFN-gamma, MIF, IL-10 and HO-1 raised
gamma-delta T cells raised
MRP8 (S100A8) and MRP14 (S100A9) raised
Procalcitonin raised
HMBG1 raised
ICAM, VCAM and p-selectin raised
insulin resistance
hyperlactataemia
hypoglycaemia
metabolic acidosis
hyponatraemia
coagulopathy
thrombocytopaenia
decreased red cell deformability