Table 1 Diagnostic classification of reference reader results used to establish accepted composite diagnosis and identify unqualified readers
Level of Diagnosis | Reported Diagnosis | Variable | Composite Diagnosis | Misdiagnosis Demerit Points |
|---|---|---|---|---|
Primary | Plasmodia positive or negative | Dichotomous | Agreement >80% | 10: false positive 5: false negative |
Secondary | Species | Discontinuous (Pf, Pv, Pm, Po)* | Agreement >80% for mono-infection Agreement >50% for mixed infection** | 3: infection misclassified |
Tertiary | Parasite Count | Continuous | Median count | 1: parasite density outside 99% CI |