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Table 3 Various dhfr/dhps combinations obtained from restriction analysis to determine point mutations in genes responsible for SP resistance.

From: Drug resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum malaria in Mlimba, Tanzania

Category

Number

Percentage (%)

Percent Cum.

tDHFR

44

36.40

36.40

dDHPS

18

14.90

51.30

tDHFR/dDHPS

24

19.80

71.10

dDHFR/dDHPS

10

8.30

79.40

tDHFR/sDHPS

4

3.30

82.70

dDHFR/sDHPS

7

5.80

88.50

tDHFR/nDHPS

14

11.50

100.00

Total

121

100.0

 
  1. tDHFR = Triple mutants on dhfr gene; dDHFR = Double mutants on dhfr gene; dDHPS = Double mutants on the dhps gene; sDHPS = Single mutant on the dhps gene; nDHPS = No mutation on the dhps gene