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Table 3 Various dhfr/dhps combinations obtained from restriction analysis to determine point mutations in genes responsible for SP resistance.

From: Drug resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum malaria in Mlimba, Tanzania

Category Number Percentage (%) Percent Cum.
tDHFR 44 36.40 36.40
dDHPS 18 14.90 51.30
tDHFR/dDHPS 24 19.80 71.10
dDHFR/dDHPS 10 8.30 79.40
tDHFR/sDHPS 4 3.30 82.70
dDHFR/sDHPS 7 5.80 88.50
tDHFR/nDHPS 14 11.50 100.00
Total 121 100.0  
  1. tDHFR = Triple mutants on dhfr gene; dDHFR = Double mutants on dhfr gene; dDHPS = Double mutants on the dhps gene; sDHPS = Single mutant on the dhps gene; nDHPS = No mutation on the dhps gene