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Table 3 Cytokine distribution in the Gabonese population: median TNF, IFN-γ and IL-10 levels per clinical group.

From: Total and functional parasite specific IgE responses in Plasmodium falciparum-infected patients exhibiting different clinical status

 

EC (min-max)

AI (min-max)

UM (min-max)

SM (min-max)

CM (min-max)

TNF (pg/ml)

41 (8–94)

36 (0–395)

8 (0–440)

175 (1–442)

209 (0–1520)

IFN- γ (pg/ml)

3,2 (0–8)

9,5 (0–31)

5 (0–395)

4 (0–201)

6,2 (2,5–9)

IL-10 (pg/ml)

14 (0–83)

102 (0–317)

134 (0–1380)

339 (0–5200)

95 (0–2300)

  1. EC – endemic control, AI – asymptomatic infected, UM – uncomplicated malaria, SM – severe malaria (non-cerebral), CM – cerebral malaria.
  2. Comparing group by group with the Endemic control: TNF was significantly lower in UM (p = 0,0006); IFN-γ was significantly higher in AI and CM (p = 0,02 and p = 0,007, respectively); IL-10 was significantly higher in UM (p = 0,0009), SM (p = 0,0001) and CM (p = 0,0001)
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Malaria Journal

ISSN: 1475-2875

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