Skip to main content

Advertisement

Table 3 Cytokine distribution in the Gabonese population: median TNF, IFN-γ and IL-10 levels per clinical group.

From: Total and functional parasite specific IgE responses in Plasmodium falciparum-infected patients exhibiting different clinical status

  EC (min-max) AI (min-max) UM (min-max) SM (min-max) CM (min-max)
TNF (pg/ml) 41 (8–94) 36 (0–395) 8 (0–440) 175 (1–442) 209 (0–1520)
IFN- γ (pg/ml) 3,2 (0–8) 9,5 (0–31) 5 (0–395) 4 (0–201) 6,2 (2,5–9)
IL-10 (pg/ml) 14 (0–83) 102 (0–317) 134 (0–1380) 339 (0–5200) 95 (0–2300)
  1. EC – endemic control, AI – asymptomatic infected, UM – uncomplicated malaria, SM – severe malaria (non-cerebral), CM – cerebral malaria.
  2. Comparing group by group with the Endemic control: TNF was significantly lower in UM (p = 0,0006); IFN-γ was significantly higher in AI and CM (p = 0,02 and p = 0,007, respectively); IL-10 was significantly higher in UM (p = 0,0009), SM (p = 0,0001) and CM (p = 0,0001)