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Table 1 Baseline characteristics of patients.

From: Potential impact of host immunity on malaria treatment outcome in Tanzanian children infected with Plasmodium falciparum

  SP (n = 50) AQ (n = 50)
Treatment outcome TF ACPR TF ACPR
PCR un-corrected, N (%) 35 (70) 15 (30) 22 (44) 28 (56)
PCR corrected, N (%) 34 (68) 16 (32) 19 (38) 31 (62)
Median age (months, CI) 31.5 (25.3–36) 27.5 (19–41.4) 24 (19.4–43.9) 32 (23.5–38.5)
Females (%) 31.6 38.7 41.2 68.7
Geometric mean parasite density, day0 (/ul. CI) 39.810 (28.184–56.234)* 17.865 (8.511–37.153) 28.840 (14.256–57.544) 32.359 (22.387–43.651)
Mean haemoglobin day0 (PCV, SD) 29.4 (4.8) 29.6 (5.8) 28.6 (6.5) 30.7 (5.1)
Mean temperature day0 (°C. SD) 38.8 (0.9) 38.5 (0.6) 38.5 (0.9) 39.1 (0.8)
Alpha+-thalassaemia, % 33.4 27.6 42.9 35.7
HbAS, % 15.2 12.5 10.4 9.7
  1. TF: Parasitological or clinical treatment failure, ACPR: Adequate clinical and parasitological response. SP: sulphadoxine-pyrimethamine, AQ: amodiaquine. * Significantly different from value for parasite density in ACPR group as calculated by Student's t test.