Table 1 Prevalence of mutations conferring resistance to chloroquine, sulfadoxine-pyrimethamine and atovaquone-proguanil in Plasmodium falciparum isolates from Mbeya & Matema, southern Tanzania
Gene | Mutation | N | Mutation (%) | Mixed type (%) |
|---|---|---|---|---|
Pfcrt | T76 | 86 | 37 (43) | 6 (7) |
Pfmdr1 | Y86 | 85 | 38 (44.7) | 6 (7.1) |
Dhfr | I51 | 86 | 80 (93) | 0 (0) |
N108 | 86 | 84 (97.7) | 0 (0) | |
T108 | 86 | 0 (0) | 0 (0) | |
R59 | 86 | 69 (80.2) | 6 (7) | |
V16 | 86 | 0 (0) | 0 (0) | |
L164 | 86 | 0 (0) | 0 (0) | |
Dhps | A436 | 84 | 4 (4.8) | 3 (3.6) |
G437 | 84 | 66 (78.6) | 2 (2.4) | |
E540 | 84 | 65 (77.4) | 8 (9.5) | |
G581 | 81 | 1 (1.2) | 0 (0) | |
N613 | 81 | 0 (0) | 0 (0) | |
Cytb | N268 | 85 | 0 (0) | 0 (0) |