Table 1 Validation data of the LC method for sulphadoxine and pyrimethamine tablets analysis.
From: Medicines informal market in Congo, Burundi and Angola: counterfeit and sub-standard antimalarials
Linearity | Sulphadoxine | Pyrimethamine |
|---|---|---|
Range | 10–200% | 10–200% |
Equation | Y = 26873 X - 3 | Y = 19603 X + 2 |
r2 | 0.99998 | 0.99994 |
Intra-day Precision | ||
MEANn = 6 (%RSD) | 97.2% (0.6) | 101.1% (0.5) |
MEANn = 6 (%RSD) | 96.8% (0.4) | 102.9% (0.4) |
MEANn = 6 (%RSD) | 98.0% (1.5) | 103.9% (0.7) |
Inter-day Precision | ||
MEANn = 3 (%RSD) | 97.3% (0.6) | 102.6% (1.4) |
Accuracy | ||
Linear equation (measured % vs added %) | Y = 1.05 X + 97.9 | Y = 1.01 X + 100.7 |
r2 | 0.998 | 0.99994 |