Skip to main content

Table 2 Clinical and laboratory adverse events probably associated with the antimalarial treatment by study group that were recorded at least once during follow up.

From: Artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Colombia

Adverse event1 Amodiaquine/Placebo Amodiaquine/Artesunate
  N = 34 (%) N = 31 (%)
Leucopaenia 18 (52,9) 13 (41,9)
Neutropaenia 16 (47,1) 15 (48,4)
Anaemia 10 (29,4) 7 (22,6)
ALT> 48 U/L 6 (17,6) 4 (12,9)
Vomit 5 (14,7) 2 (6,5)
Dizziness 5 (14,7) 6 (19,4)
Abdominal pain 5 (14,7) 4 (12,9)
Bilirubin >1 mg/dL 5 (14,7) 6 (19,4)
Itching 4 (11,8) 4 (12,9)
Headache 3 (8,8) 0 (0)
Diarrhoea 2 (5,9) 2 (6,5)
Anorexia 2 (5,9) 1 (3,2)
Nausea 1 (2,9) 3 (9,7)
  1. 1Definitions: leucopaenia (WBC<5,000/mm3), neutropaenia (total neutrophils<2,000/mm3), anaemia (haemoglobin <12 g/dL). ALT: Alanine Amino Transferase