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Table 2 Clinical and laboratory adverse events probably associated with the antimalarial treatment by study group that were recorded at least once during follow up.

From: Artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Colombia

Adverse event1

Amodiaquine/Placebo

Amodiaquine/Artesunate

 

N = 34

(%)

N = 31

(%)

Leucopaenia

18

(52,9)

13

(41,9)

Neutropaenia

16

(47,1)

15

(48,4)

Anaemia

10

(29,4)

7

(22,6)

ALT> 48 U/L

6

(17,6)

4

(12,9)

Vomit

5

(14,7)

2

(6,5)

Dizziness

5

(14,7)

6

(19,4)

Abdominal pain

5

(14,7)

4

(12,9)

Bilirubin >1 mg/dL

5

(14,7)

6

(19,4)

Itching

4

(11,8)

4

(12,9)

Headache

3

(8,8)

0

(0)

Diarrhoea

2

(5,9)

2

(6,5)

Anorexia

2

(5,9)

1

(3,2)

Nausea

1

(2,9)

3

(9,7)

  1. 1Definitions: leucopaenia (WBC<5,000/mm3), neutropaenia (total neutrophils<2,000/mm3), anaemia (haemoglobin <12 g/dL). ALT: Alanine Amino Transferase