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Table 2 Parameter estimates obtained from fitting the 3-parameter sigmoid curve to the most resistant isolates using standard individual data analysis (fitted using WinNonlin®).

From: Overestimating resistance in field testing of malaria parasites: simple methods for estimating high EC50 values using a Bayesian approach

Isolate Parameter estimates (% CV)
  EC 50 γ Emax EC 50 *
Artesunate (A) 23.3(22) 12.5(65) 0.95 (2) 23.4 (12)
Halofantrine (B) 51.8(51564) 27.9 (225370) 1.10 (5) 50.1 (37)
Mefloquine (C) 195 (4160) 21.1 (25309) 1.15 (2) 175 (17)
Mefloquine (D) 197 (2014) 17.1 (12967) 1.25 (6) 178 (52)
Chloroquine (E) 1065 (18) 7.98 (68) 0.79 (4.2) 1065 (18)
Chloroquine (F) 536 (6) 3.5 (18) 0.92 (2.4) 536 (6)
  1. * – estimates obtained by fitting model with boundary (-10,10) for γ