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Table 5 Methodological differences in the estimation of antimalarial resistance; the highest EC50 (ng/mL) (Brockman et al, 2000)

From: Overestimating resistance in field testing of malaria parasites: simple methods for estimating high EC50 values using a Bayesian approach

Isolate Range of concentrations tested (ng/mL) EC 50 Standard estimate EC 50 "Bayesian" estimate Overestimation by standard method (%)
Artesunate (A) 0.52 – 33.46 23.4 20.3 15%
Halofantrine (B) 1.02 – 65.32 51.8 41.2 26%
Mefloquine (C) 3.59 – 230 195 138 41%
Mefloquine (D) 3.59 – 230 197 138 43%
Chloroquine (E) 21.44 – 1,372 1065 801 32%
Chloroquine (F) 21.44 – 683 536 420 32%