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Table 2 Enrollment clinical data and therapeutic responses of patients with acute uncomplicated Plasmodium falciparum treated with chloroquine stratified by age

From: Rapid detection of Pfcrt and Pfmdr1 mutations in Plasmodium falciparum isolates by FRET and in vivo response to chloroquine among children from Osogbo, Nigeria

Age Freq Sex Temp Mean Mean Mean T76 Y86 F184 CQ Treatment
(Yrs)   M F (SD) PD FC PC (%) (%) (%) Cured Failed
0<4 72 39 33 37.7 (± 1.13) 8261.066 2.7 2.6 67 (93%) 27 (38%) 49 (68%) 46 (58%) 26 (36%)
4<8 27 20 7 38.0 (± 1.3) 11632.6 1.2 2.4 22 (81%) 9 (33%) 20 (74%) 17 (63%) 10 (37%)
8–12 17 10 7 37.8 (± 0.84) 9015.282 1.3 2.5 16 (94%) 6 (35%) 12 (71%) 9 (53%) 8 (47%)
Total 116 69 47 37.8 (± 1.3) 9061.375 1.7 2.5 102 (88%) 42 (36%) 81 (70%) 72 (62%) 44 (38%)
  1. Key: Freq = Frequency
  2. SD = Standard deviation
  3. PD = Parasite density on Day 0
  4. FC = Fever clearance time in days
  5. PC = Parasite clearance time in days