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Table 2 Enrollment clinical data and therapeutic responses of patients with acute uncomplicated Plasmodium falciparum treated with chloroquine stratified by age

From: Rapid detection of Pfcrt and Pfmdr1 mutations in Plasmodium falciparum isolates by FRET and in vivo response to chloroquine among children from Osogbo, Nigeria

Age

Freq

Sex

Temp

Mean

Mean

Mean

T76

Y86

F184

CQ Treatment

(Yrs)

 

M

F

(SD)

PD

FC

PC

(%)

(%)

(%)

Cured

Failed

0<4

72

39

33

37.7 (± 1.13)

8261.066

2.7

2.6

67 (93%)

27 (38%)

49 (68%)

46 (58%)

26 (36%)

4<8

27

20

7

38.0 (± 1.3)

11632.6

1.2

2.4

22 (81%)

9 (33%)

20 (74%)

17 (63%)

10 (37%)

8–12

17

10

7

37.8 (± 0.84)

9015.282

1.3

2.5

16 (94%)

6 (35%)

12 (71%)

9 (53%)

8 (47%)

Total

116

69

47

37.8 (± 1.3)

9061.375

1.7

2.5

102 (88%)

42 (36%)

81 (70%)

72 (62%)

44 (38%)

  1. Key: Freq = Frequency
  2. SD = Standard deviation
  3. PD = Parasite density on Day 0
  4. FC = Fever clearance time in days
  5. PC = Parasite clearance time in days