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Table 1 Properties of hypothetical vaccines

From: Measures of clinical malaria in field trials of interventions against Plasmodium falciparum

   

Vaccine effect

  

Placebo

A: Reduction in force of infection by 50%

B: Reduction in parasite densities by 50%

C: Multi-plication of pyrogenic threshold by 2

Prevalence of patent infection

80%

40%

77%

80%

Relative incidence of disease

All episodes

100.0

77.2

74.0

74.0

 

Malaria

45.5

22.8

19.6

19.6

 

Non malaria

54.5

54.5

54.5

54.5

True efficacy in preventing clinical malaria episodes

-

50%

57%

57%

True efficacy in preventing any disease episode

-

22.8%

26.0%

26.0%