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Table 4 Frequency of individuals with molecular makers associated to SP resistance, Lainé refugee camp

From: Efficacy of antimalarial treatment in Guinea: in vivo study of two artemisinin combination therapies in Dabola and molecular markers of resistance to sulphadoxine-pyrimethamine in N'Zérékoré

Prevalence No of individuals (Single+majority+mixed aplotypes) % 95% CI
dhps (N = 135)    
Double mutant 437&540 14 (6+2+6) 10.4 5.8–16.8
Double mutant 436&437 36 (22+7+7) 26.7 19.4–35.0
dhfr (N = 160)    
triple mutant 51–59–108 137 (121+5+11) 85.6 79.2–90.7
dhfr and dhps (N = 135)    
triple mutant 51–59–108 with double mutant 437&540 13 (6+2+5) 9.6 5.2–15.9
  1. Single aplotype: only one single nucleotide polymorphism (SNP) was present
  2. Majority aplotype: volume minority SNP value was more than half of the volume of the majority SNP
  3. Mixed aplotype: volume minority SNP value was less than half of the volume of the majority SNP [9]