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Table 3 Proportion of children with continued false-positive (FP) RDTs, stratified by day-0 parasite density

From: Paracheck-Pf® accuracy and recently treated Plasmodium falciparum infections: is there a risk of over-diagnosis?

Parasite density

(× 103), Day 0

Day 7 % FP

(95% CI)

Day 14 % FP

(95% CI)

Day 21 % FP

(95% CI)

Day 28 % FP

(95% CI)

Day 35 % FP*

(95% CI)

50–200 (n = 30)

100

100

100

100

77.3 (17/22)

 

-

-

-

-

(54.6–92.2)

20–50 (n = 42)

100

100

97.6 (41/42)

97.6 (41/42)

79.2 (19/24)

 

-

-

(87.4–99.9)

(87.4–99.9)

(57.8–92.9)

10–20 (n = 22)

100

100

100

90.9 (20/22)

71.4 (10/14)

 

-

-

-

(70.9–98.9)

(46.2–95.0)

2–10 (n = 18)

94.4 (17/18)

88.9 (16/18)

72.2 (13/18)

66.7 (12/18)

50.0 (4/8)

 

(72.7–99.9)

(65.3–98.6)

(46.5–90.3)

(41.0–86.7)

(15.7–84.3)

Total

99.1 (111/112)

98.2 (110/112)

94.6 (106/112)

92.0 (103/112)

73.5 (50/68)

 

(95.1–100)

(93.7–99.8)

(88.7–98.0)

(85.3–96.3)

(61.4–83.5)

  1. *44 children were not able to complete a day-28 clinic visit after forced evacuation of the study team due to political insecurity in the region.