Figure 3
From: Germinal center architecture disturbance during Plasmodium berghei ANKA infection in CBA mice
Spleen/Lymph nodes. A) Spleen T cell zone of infected mouse (day 6). Intense plasmacytogenesis with mitotic figures (arrows). Giemsa. B) Spleen T cell zone of infected mouse (day 10). Intense plasmacytogenesis at a more advanced stage, with plasma cell (arrow) differentiation. Giemsa. C) Lymph node of non-infected control mouse. Panoramic view of the paracortical (Pc) and follicular (Flc) areas. Giemsa. Arrows: high endothelial venules with trafficking lymphocytes. D) Detail of lymph node paracortical area of non-infected control mouse, showing interdigitating cells (arrows). Giemsa. E) Detail of lymph node paracortical area of infected mouse (day 3). Many immunoblasts (arrows). Giemsa. F) Lymph node of infected mouse (day 3). Immunoblasts (white arrows) and high endothelial venules (black arrows) showing trafficking lymphocytes. Giemsa.