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Table 2 Leukocyte aggregation-inducing effects of lipid fractions of Plasmodium vivax paroxysm plasma and of P. vivax schizont extracts with or without supplementation with recombinant human cytokines (TNFα, GM-CSF, IL-6 and IL-10).

From: Plasmodium vivax: paroxysm-associated lipids mediate leukocyte aggregation

Expt. No. Sample % R CAI (Median) 25% 75%
1 P1 26.30 20.10 30.60
2 P2 4.50 3.40 8.60
3 P3 4.20 3.50 6.40
4 P4 8.50 6.80 11.80
5 P5 1.00 0.20 1.30
6 P1 + Cytokines 38.20 34.20 46.50
7 P2 + Cytokines 8.70 5.60 10.90
8 P3 + Cytokines 8.60 4.60 12.40
9 P4 + Cytokines 24.60 22.50 31.70
10 P5 + Cytokines 1.20 0.50 3.60
11 S1 3.1 1.4 6.4
12 S2 2.5 1.3 5.9
13 S3 2.9 1.2 7.4
14 S4 14.3 12.3 18.6
15 S5 1 0.2 2.4
16 S1 + Cytokines 10.4 7.6 13.9
17 S2 + Cytokines 3.8 2.5 6.4
18 S3 + Cytokines 2.7 1.9 6.5
19 S4 + Cytokines 26.2 21.9 30.4
20 S5 + Cytokines 1.1 0.3 2.1
  1. % RCAI: % Relative Cell Aggregation Index (median)
  2. 25%–75%: 25th and 75th percentiles
  3. Different fractions of P. vivax schizont extracts (S1 – acetone fraction, S2 – ethanol fraction, S3 – petroleum ether fraction, S4 – diethyl ether fraction and S5 – remaining fraction ) and similar fractions of paroxysm plasma ( P1 – acetone fraction, P2 – ethanol fraction, P3 – petroleum ether fraction, P4 – diethyl ether fraction and P5 – remaining fraction ) were tested for their ability to induce cell aggregation with or without supplementation with recombinant human cytokines (TNFα, GM-CSF, IL-6 and IL-10).
  4. The table provides the median values together with the interquartile range (25%–75%).