Skip to main content

Table 3 Clinical tolerance after one or two administrations of IRQA.

From: Acceptability and efficacy of intra-rectal quinine alkaloids as a pre-transfer treatment of non-per os malaria in peripheral health care facilities in Mopti, Mali

After 1st Intra rectal administration Peripheral care unit (N = 130) Referral care unit (N = 130)  
  % % p-value
Skin with dehydration marks 3.8 16.2 < 0.01
Abnormal anal margin 2.3 3.1 ns
Blood in stools 0.8 0.8 ns
  N = 115 N = 115  
Liquid/semi liquid stools 25.2 75.7 < 0.01
  After 1st dose After 2nd dose  
  N = 47 N = 47  
  % % p-value
Skin with dehydration marks 4.3 6.4 ns
Abnormal anal margin 2.1 - ns
Blood in stools 0.8 0.8 ns
Liquid/semi liquid stools 19.1 44.7 < 0.01
  1. More children had liquid/semi liquid stools after the first administration of IRQA. The second administration was better tolerated.