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Table 1 Lymphocyte subset frequencies (median percentages [95% confidence intervals]*) in Burkitt's lymphoma patients and healthy control donors

From: Selective activation of TCR-γδ+ cells in endemic Burkitt's lymphoma

Subset   Healthy controls eBL patients Difference P(T)*
CD3+** - 81.7 [76.4 to 86.4] 66.5 [47.6 to 72.1] -15.4 [-34.1 to -7.5] <0.001
CD19+** - 0.4 [0.2 to 1.0] 5.8 [4.8 to 8.8] 5.4 [4.2 to 8.4] <0.001
CD3+ CD4+ 63.5 [53.6 to 65.7] 68.0 [57.8 to 75.0] 5.0 [-1.9 to 13.1] 0.11
CD3+ CD8+ 27.8 [26.6 to 31.7] 20.9 [16.6 to 29.7] -6.0 [-11. 5 to 1.8] 0.08
CD3+ TCR-γδ+ 7.5 [4.9 to 15.5] 3.3 [2.6 to 5.4] -3.6 [-7.9 to -1.2] 0.006
TCR-γδ+ Vγ 9+ 45.2 [34.8 to 59.8] 18.8 [14.2 to 29.8] -25.2 [-35.4 to -15.1] <0.001
TCR-γδ+ V δ 2+ 32.3 [12.3 to 45.1] 9.2 [6.9 to 13.9] -2 1.2 [-3 1.2 to -4.8] 0.007
TCR-γδ+ V δ 3+ 7.7 [5.0 to 11. 7] 9.8 [5.4 to 14.3] 2.2 [-1.9 to 6.6] 0.25
TCR-γδ+ CD4+ 4.8 [3.7 to 9.6] 7.5 [4.9 to 34.8] 2.9 [0.1 to 24.2] 0.04
TCR-γδ+ CD8+ 31.2 [26.4 to 48.3] 36.6 [26.0 to 45.9] 0.0 [-8.0 to 11.0] 0.98
  1. * The statistical significance of differences in medians was calculated by the Mann-Whitney rank-sum test. Confidence intervals for median differences were calculated using CIA 2.0 software [1].
  2. ** Of all lymphocytes identified by forward and side scatter properties