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Table 1 Lymphocyte subset frequencies (median percentages [95% confidence intervals]*) in Burkitt's lymphoma patients and healthy control donors

From: Selective activation of TCR-γδ+ cells in endemic Burkitt's lymphoma

Subset

 

Healthy controls

eBL patients

Difference

P(T)*

CD3+**

-

81.7 [76.4 to 86.4]

66.5 [47.6 to 72.1]

-15.4 [-34.1 to -7.5]

<0.001

CD19+**

-

0.4 [0.2 to 1.0]

5.8 [4.8 to 8.8]

5.4 [4.2 to 8.4]

<0.001

CD3+

CD4+

63.5 [53.6 to 65.7]

68.0 [57.8 to 75.0]

5.0 [-1.9 to 13.1]

0.11

CD3+

CD8+

27.8 [26.6 to 31.7]

20.9 [16.6 to 29.7]

-6.0 [-11. 5 to 1.8]

0.08

CD3+

TCR-γδ+

7.5 [4.9 to 15.5]

3.3 [2.6 to 5.4]

-3.6 [-7.9 to -1.2]

0.006

TCR-γδ+

Vγ 9+

45.2 [34.8 to 59.8]

18.8 [14.2 to 29.8]

-25.2 [-35.4 to -15.1]

<0.001

TCR-γδ+

V δ 2+

32.3 [12.3 to 45.1]

9.2 [6.9 to 13.9]

-2 1.2 [-3 1.2 to -4.8]

0.007

TCR-γδ+

V δ 3+

7.7 [5.0 to 11. 7]

9.8 [5.4 to 14.3]

2.2 [-1.9 to 6.6]

0.25

TCR-γδ+

CD4+

4.8 [3.7 to 9.6]

7.5 [4.9 to 34.8]

2.9 [0.1 to 24.2]

0.04

TCR-γδ+

CD8+

31.2 [26.4 to 48.3]

36.6 [26.0 to 45.9]

0.0 [-8.0 to 11.0]

0.98

  1. * The statistical significance of differences in medians was calculated by the Mann-Whitney rank-sum test. Confidence intervals for median differences were calculated using CIA 2.0 software [1].
  2. ** Of all lymphocytes identified by forward and side scatter properties