Table 1 Comparison of course of infection of P. chabaudi (ER) in mice that were infected with known number of sporozoites with those infected via the bite of infectious mosquitoes.
| Mice | Parasitaemia | |||||
|---|---|---|---|---|---|---|
| Patency (day) | Peak (day) | Peak (%) | Duration (days) | |||
| Numbers of sporozoites injected (i.v.) | 100 | 1 | 5 | 13 | 3.86 | 15 |
| 2 | 6 | 6 | 0.0114 | 1 | ||
| n ± SEM | 5.5 ± 0.1 | 9.5 ± 3.5 | 1.9 ± 1.9 | 8 ± 7.0 | ||
| 500 | 1 | 5 | 11 | 3.35 | 9 | |
| 2 | 5 | 11 | 1.4 | 11 | ||
| 3 | 5 | 11 | 4.96 | 15 | ||
| n ± SEM | 5.0 ± 0.0 | 11.0 ± 0.3 | 3.2 ± 1 | 11.7 ± 1.8 | ||
| 1000 | 1 | 5 | 11 | 5.41 | 15 | |
| 2 | 5 | 11 | 3.9 | 11 | ||
| 3 | 5 | 10 | 3.9 | 13 | ||
| n ± SEM | 5.0 ± 0.0 | 10.7 ± 0.3 | 4.4 ± 0.5 | 13.0 ± 1.2 | ||
| 16000 | 1 | 5 | 8 | 7.4 | 13 | |
| Mosquito bite | n ± SEM | 6.8 ± 0.6 | 11.5 ± 1.6 | 5.5 ± 2.5 | 9.8 ± 2.0 | |