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Table 1 Comparison of course of infection of P. chabaudi (ER) in mice that were infected with known number of sporozoites with those infected via the bite of infectious mosquitoes.

From: Cytokine responses of CD4+ T cells during a Plasmodium chabaudi chabaudi (ER) blood-stage infection in mice initiated by the natural route of infection

  

Mice

Parasitaemia

   

Patency (day)

Peak (day)

Peak (%)

Duration (days)

Numbers of sporozoites injected (i.v.)

100

1

5

13

3.86

15

  

2

6

6

0.0114

1

  

n ± SEM

5.5 ± 0.1

9.5 ± 3.5

1.9 ± 1.9

8 ± 7.0

 

500

1

5

11

3.35

9

  

2

5

11

1.4

11

  

3

5

11

4.96

15

  

n ± SEM

5.0 ± 0.0

11.0 ± 0.3

3.2 ± 1

11.7 ± 1.8

 

1000

1

5

11

5.41

15

  

2

5

11

3.9

11

  

3

5

10

3.9

13

  

n ± SEM

5.0 ± 0.0

10.7 ± 0.3

4.4 ± 0.5

13.0 ± 1.2

 

16000

1

5

8

7.4

13

Mosquito bite

n ± SEM

6.8 ± 0.6

11.5 ± 1.6

5.5 ± 2.5

9.8 ± 2.0