Skip to main content

Table 1 Comparison of course of infection of P. chabaudi (ER) in mice that were infected with known number of sporozoites with those infected via the bite of infectious mosquitoes.

From: Cytokine responses of CD4+ T cells during a Plasmodium chabaudi chabaudi (ER) blood-stage infection in mice initiated by the natural route of infection

   Mice Parasitaemia
    Patency (day) Peak (day) Peak (%) Duration (days)
Numbers of sporozoites injected (i.v.) 100 1 5 13 3.86 15
   2 6 6 0.0114 1
   n ± SEM 5.5 ± 0.1 9.5 ± 3.5 1.9 ± 1.9 8 ± 7.0
  500 1 5 11 3.35 9
   2 5 11 1.4 11
   3 5 11 4.96 15
   n ± SEM 5.0 ± 0.0 11.0 ± 0.3 3.2 ± 1 11.7 ± 1.8
  1000 1 5 11 5.41 15
   2 5 11 3.9 11
   3 5 10 3.9 13
   n ± SEM 5.0 ± 0.0 10.7 ± 0.3 4.4 ± 0.5 13.0 ± 1.2
  16000 1 5 8 7.4 13
Mosquito bite n ± SEM 6.8 ± 0.6 11.5 ± 1.6 5.5 ± 2.5 9.8 ± 2.0