Table 1 Publications on the activity of ferroquine against P. falciparum isolates
Drug IC50 (Geometric mean) | |||||||
|---|---|---|---|---|---|---|---|
Year | Country | Region | No. of isolates | Ferroquine | Chloroquine | Method | |
Pradine et al. [10] | 2001 | Gabon | Libreville | 103 | 10.8 nM | 370 nM | Isotopic microtest |
Atteke et al. [12] | 2003 | Gabon | Franceville | 56 | 16.0 nM | 141.3 nM | Isotopic microtest |
Bakoumba | 60 | 27.9 nM | 398.0 nM | ||||
Pradine et al. [11] | 2002 | Senegal | 55 | 7.9 nM | 102 mM | Isotopic microtest | |
Chim et al. [13] | 2004 | Cambodia | 127 | 30.61 nM | 125.04 nM | Isotopic microtest | |