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Table 3 Correlation of antibody responses to MSP2 recombinant antigens expressing allelic family specific and conserved regions; a, antibodies in all patients b, antibodies in naïve patients

From: Antibodies elicited in adults by a primary Plasmodium falciparum blood-stage infection recognize different epitopes compared with immune individuals

   

Pearson's correlation coefficients (r)

 
 

3D7 non-repetitive

FC27

FC27 non-repetitive

MSP2 conserved region

All infections (n = 20, 2 non-typeable)

    

3D7

0.96a

0.51b

0.42

0.55b

3D7 non-repetitive

 

0.48b

0.4

0.67a

FC27

  

0.85a

0.13

FC27 non-repetitive

   

0.27

All single allelic family infections (n = 15)

    

3D7

0.94a

0.55b

0.18

0.33

3D7 non-repetitive

 

0.48

0.17

0.51

FC27

  

0.83a

0.13

FC27 non-non-repetitive

   

0.17

Single 3D7 infections (n = 11)

    

3D7

0.95a

0.89a

0.78b

0.6

3D7 non-repetitive

 

0.82b

0.85a

0.72b

FC27

  

0.57

0.43

FC27 non-repetitive

   

0.92a

Single FC27 infections (n = 4)

    

3D7

0.96b

0.33

-0.14

-0.35

3D7 non-repetitive

 

0.39

-0.12

-0.24

FC27

  

0.87

-0.81

FC27 non-repetitive

   

-0.78

Multiple 3D7/FC27 infections (n = 3)

    

3D7

0.98

0.79

0.89

0.63

3D7 non-repetitive

 

0.67

0.79

0.76

FC27

  

0.98

0.03

FC27 non-repetitive

0.21

   
  1. a p < 0.001
  2. b p < 0.05