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Table 1 Host polymorphism and parasitological data for 555 children from the Amele region, Papua New Guinea

From: Host erythrocyte polymorphisms and exposure to Plasmodium falciparum in Papua New Guinea

  

P. falciparum Prevalencea

 

Host Polymorphism

 

Negative

Positive

Positive

 
 

Frequency

Both surveys

One survey

Both surveys

P b

 

n (%)

n (%)

n (%)

n(%)

 

α+-Thalassaemia

   (αα/αα)

39 (7.1)

15 (38.5)

19 (48.7)

5 (12.8)

.

   (-α/αα)

205 (36.9)

75 (37.1)

94 (46.5)

33 (16.3)

0.72

   (-α/-α)

311(56.0)

125 (41.7)

120 (40.0)

55 (18.3)

0.99

CR1c

   HH

29 (5.4)

14 (48.3)

12 (41.4)

3 (10.3)

.

   HL

188 (35.5)

70 (38.0)

78 (42.4)

36 (19.6)

0.07

   LL

313 (59.1)

121 (39.9)

133 (43.9)

49 (16.2)

0.11

ABOc

   O

180 (32.6)

69 (39.4)

66 (37.7)

40 (22.9)

.

   non-O

372 (67.4)

145 (39.9)

165 (45.5)

53 (14.6)

0.09

   A

178 (32.2)

62 (35.6)

80 (46.0)

32 (18.4)

0.83

   B

138 (25.0)

62 (46.6)

58 (43.6)

13 (9.8)

0.005

   AB

56 (10.1)

21 (37.5)

27 (48.2)

8 (14.3)

0.27

SAOc

   Normal

506 (91.2)

200 (40.4)

211 (42.6)

84 (17.0)

.

   SAO

49 (8.8)

15 (32.6)

22 (47.8)

9 (19.6)

0.29

G6PDc

   Normal

477 (89.7)

182 (39.1)

199 (42.7)

85 (18.2)

.

   Intermediate

20 (3.8)

8 (44.4)

6 (33.3)

4 (22.2)

0.76

   Deficient

35 (6.6)

16 (45.7)

16 (45.7)

3 (8.6)

0.36

  1. aMissing data: 1999, n = 1; 2000, n = 21.
  2. bDifferences in frequency of positive slides were assessed using ordinal regression with adjustments for age.
  3. c Abbreviations: CR1, Complement receptor 1; SAO, Southeast Asian Ovalocytosis; G6PD, Glucose-6-phosphate dehydrogenase deficiency. With the exception of SAO, these variables contain missing values.