Skip to main content

Table 1 Host polymorphism and parasitological data for 555 children from the Amele region, Papua New Guinea

From: Host erythrocyte polymorphisms and exposure to Plasmodium falciparum in Papua New Guinea

   P. falciparum Prevalencea  
Host Polymorphism   Negative Positive Positive  
  Frequency Both surveys One survey Both surveys P b
  n (%) n (%) n (%) n(%)  
α+-Thalassaemia
   (αα/αα) 39 (7.1) 15 (38.5) 19 (48.7) 5 (12.8) .
   (-α/αα) 205 (36.9) 75 (37.1) 94 (46.5) 33 (16.3) 0.72
   (-α/-α) 311(56.0) 125 (41.7) 120 (40.0) 55 (18.3) 0.99
CR1c
   HH 29 (5.4) 14 (48.3) 12 (41.4) 3 (10.3) .
   HL 188 (35.5) 70 (38.0) 78 (42.4) 36 (19.6) 0.07
   LL 313 (59.1) 121 (39.9) 133 (43.9) 49 (16.2) 0.11
ABOc
   O 180 (32.6) 69 (39.4) 66 (37.7) 40 (22.9) .
   non-O 372 (67.4) 145 (39.9) 165 (45.5) 53 (14.6) 0.09
   A 178 (32.2) 62 (35.6) 80 (46.0) 32 (18.4) 0.83
   B 138 (25.0) 62 (46.6) 58 (43.6) 13 (9.8) 0.005
   AB 56 (10.1) 21 (37.5) 27 (48.2) 8 (14.3) 0.27
SAOc
   Normal 506 (91.2) 200 (40.4) 211 (42.6) 84 (17.0) .
   SAO 49 (8.8) 15 (32.6) 22 (47.8) 9 (19.6) 0.29
G6PDc
   Normal 477 (89.7) 182 (39.1) 199 (42.7) 85 (18.2) .
   Intermediate 20 (3.8) 8 (44.4) 6 (33.3) 4 (22.2) 0.76
   Deficient 35 (6.6) 16 (45.7) 16 (45.7) 3 (8.6) 0.36
  1. aMissing data: 1999, n = 1; 2000, n = 21.
  2. bDifferences in frequency of positive slides were assessed using ordinal regression with adjustments for age.
  3. c Abbreviations: CR1, Complement receptor 1; SAO, Southeast Asian Ovalocytosis; G6PD, Glucose-6-phosphate dehydrogenase deficiency. With the exception of SAO, these variables contain missing values.