Figure 1

Parity-dependency of the plasma antibody reactivity to VAR2CSA and MSP1 ₁₉ recombinant proteins. ELISA was carried out on DBL5ε- and MSP1₁₉ coated plates. IgG, IgG1, IgG2, IgG3, and IgG4 directed against DBL5ε-, as well as against MSP1₁₉ . Antibody plasma levels are expressed as arbitrary units (AU) and are shown at enrolment and at delivery for primigravid (panel A, n = 53) and multigravid women (panel B, n = 185) from Senegal. The top, bottom, and line through the middle of the box correspond to the 75^th percentile, 25^th percentile, and 50^th percentile (median), respectively. The whiskers on the bottom extend from the 10^th percentile and top 90^th percentile.