Full blood count and haemozoin-containing leukocytes in children with malaria: diagnostic value and association with disease severity

Table 3 Comparison of microscopic and automated detection of Hz-containing leukocytes

	non-severe malaria (n = 104)	severe malaria* (n = 48)	severe anaemia (n = 15)	cerebral malaria (n = 17)
Patients with PCM
Microscopy	91.3%	100%	100%	100%
Cell-Dyn 3000^®	94.3%	100%	100%	100%
P	NS	NS	NS	NS
Patients with PCN
Microscopy	56,7%	91,7%	80,0%	100%
Cell-Dyn 3000^®	80,7%	96,8%	86,7%	100%
P	p < 0,0001	NS	NS	NS

Microscopy: Observation of 200 granulocytes and 100 monocytes in Giemsa-stained thick film. The Cell-Dyn 3000^® analysed a mean of 4,175 granulocytes (range: 800–8,830) and a mean of 1,364 monocytes (range: 230–3,660).
* Severe malaria includes the following cases: severe malaria (n = 15) and cerebral malaria (n = 17), as shown in two right colums; hyperparasitaemia (n = 13), hypoglycaemia (n = 3).
P = chi square test, NS: not significant (>0,05)

ISSN: 1475-2875