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Table 1 Developmental expression of surf genes as seen by RT-PCR using primer set 1. surf genes exhibit a differential expression pattern during the different stages of the parasite cycle.

From: SURFIN4.1, a schizont-merozoite associated protein in the SURFIN family of Plasmodium falciparum

surf Gene   Time Post Invasion (hrs) SURFIN Grouping§
  PlasmoDB ID 10 20 30 40  
surf 1.1 PFA0625w - - + + A
surf 1.2 PFA0650w - - - - Truncated
surf 1.3 PFA0725w + + + + B
surf 4.1 PFD0105c, PFD0100c - - + + A
surf 4.2 PFD1160w + + + + A
surf 8.1 MAL8P1.1 - - - - B
surf 8.2 PF08_0002 - - - - A
surf 8.3 MAL8P1.162 + + + + B
surf 13.1 PF13_0074, PF13_0075 - - - - Truncated
surf 14.1 PF14_0747 - - + - B
  1. The genes that are expressed are indicated by "+" while those that are not expressed are indicated by "-". surf4.1 is expressed in the late stages of the cycle from ≈30 hrs all the way until the dividing merozoites. Three surf genes (surf1.3, surf4.2 and surf8.3) are expressed throughout the life cycle while others are expressed at a particular stage in the life cycle.
  2. + = Gene amplified.
  3. - = Gene not amplified.
  4. §SURFIN grouping is based on the number of exons [20] as well as protein alignments which have resulted in surf4.1 to be in group A even though it has 3 exons. The transmembrane domain in the group A paralogs is present in the first exon and in the second exon in group B paralogs