Antimalarial drug use in general populations of tropical Africa

Malaria Journal

Table 5 Multivariate analysis of the presence of chloroquine in urines of children between two and nine years of age.

Variables	N	CQ+*	Prevalence of CQ † %	Crude OR	95%CI		p‡	Adjusted OR	95%CI		p‡
Age
2–5 years old	1419	691	49	1.00				1.00
6–9 years old	1633	571	35	0.74	0.09	0.63	0.001	0.76	0.64	0.90	0.002
Fever during the preceding 3 days
without	2252	852	38	1.00				1.00
with	800	410	51	1.24	1.02	1.50	0.032	1.22	1.01	1.49	0.043
Proportion of individuals who were living in an other locality one year before the study
< 5%	1424	471	33	1.00				1.00
>= 5%	1628	791	49	2.29	0.97	5.40	0.058	2.53	1.38	4.64	0.003
Score in 2 classes representing the households' average socioeconomic level
< 6	2540	914	36	1.00				1.00
>= 6	512	349	68	4.73	1.74	12.87	0.002	2.74	1.11	6.78	0.029
Prevalence rate of the anti-CSP antibodies
< 20%	635	245	39	1.00				1.00
20–39.9%	1227	746	61	2.82	1.11	7.16	0.0289	2.47	1.13	5.41	0.023
>= 40%	1190	271	23	0.44	0.17	1.12	0.0885	0.68	0.32	1.43	0.305
Duration of the route to join the nearest tarmacked road
< 1 hour	1336	640	48	1.00				1.00
>= 1 hour	1716	622	36	0.56	0.23	1.37	0.206	0.49	0.27	0.89	0.019

*CQ+ = number of samples with chloroquine in urines, † CQ: Chloroquine, ‡ p: p-value
Logistic regression model with random effect taking into account the interdependency of observations made within the same site.

ISSN: 1475-2875