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Table 2 Correlation of TNF levels with genotypes of the -1031 and -863 SNPs in controls and patients. Comparison of means was carried out by Kruskal-Wallis test.

From: Polymorphisms of TNF-enhancer and gene for FcγRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population

  TNF levels as mean ± S.D. (pg/ml)
  Controls (n = 100) Patients (n = 111)
-1031     
   TT 18.2 ± 22.17 (n = 58) P = 0.0178 27.9 ± 29.14 (n = 58) P = 0.0089
   TC 21.3 ± 23.2 (n = 36)   40.9 ± 64.9 (n = 47)  
   CC 56.56 ± 35.1 (n = 6)a   126.6 ± 80.82 (n = 6)b  
-863     
   CC 19.01 ± 22.9 (n = 61) P = 0.0481 25.6 ± 29.3 (n = 62) P = 0.0231
   CA 17.79 ± 17.9 (n = 30)   47.5 ± 66.8 (n = 44)  
   AA 52.27 ± 35.1 (n = 9)c   124.7 ± 90.2 (n = 5)d  
  1. 'n' indicates number of individuals in each category.
  2. a,b TNF levels in TT vs. CC in controls and patients: P < 0.01 (Mann-Whitney test)
  3. c,d TNF levels in CC vs. AA in controls and patients: P < 0.02 (Mann-Whitney test)
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Malaria Journal

ISSN: 1475-2875

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