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Table 1 Cytoadherence of differently selected 3D7 parasites selected for adhesion on the indicated CHO-cell lines

From: Var transcription profiling of Plasmodium falciparum 3D7: assignment of cytoadherent phenotypes to dominant transcripts

  CHO-745 CHO-K1 CHO-CD36 CHO-ICAM CHO-Sel CHO-VCAM
3D7 7 ± 2 0 12 ± 4 7 ± 3 5 ± 1 4 ± 2
3D7-745 142 ± 13 120 ± 23 15 ± 3 253 ± 22 28 ± 5 270 ± 26
3D7-K1 25 ± 3 29 ± 5 32 ± 8 45 ± 8 45 ± 3 34 ± 4
3D7-CD36* 16 ± 3 3 ± 1 62 ± 7 33 ± 5 25 ± 5 23 ± 6
3D7-ICAM* 40 ± 9 40 ± 7 152 ± 12 235 ± 18 141 ± 13 151 ± 17
3D7-Selectin 13 ± 2 16 ± 3 21 ± 5 50 ± 8 34 ± 3 15 ± 5
3D7-VCAM 51 ± 11 51 ± 8 92 ± 12 226 ± 21 151 ± 14 51 ± 5
  1. A stock of freshly panned parasites was thawed, put into culture and after 4–6 reinvasions, 5*106 IRBC (at trophozoite stage) were incubated on the indicated CHO-cell lines, washed and counted. For each cell line, 1000 cells and the adhering parasites were counted and cytoadherence was expressed as IRBC per 100 cells. Phenotypes which significantly (Chi-square method, p < 0,05) adhered more to the CHO cell line for which they were selected than to any other cell line are marked with an asterisk.