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Table 2 Association of total IgG and IgM with malaria incidence

From: Cohort study of the association of antibody levels to AMA1, MSP119, MSP3 and GLURP with protection from clinical malaria in Ghanaian children

IgG Crude IRR (95%CI) P-value IRR adjusted for age (95%CI) P-value
MSP3 0.59 (0.45, 0.76) < 0.0001 0.69 (0.53, 0.90) 0.01
MSP119 0.74 (0.63, 0.88) < 0.0001 0.75 (0.61, 0.92) 0.01
GLURP 0.68 (0.55, 0.82) < 0.0001 0.79 (0.64, 0.98) 0.04
AMA1 0.96 (0.84, 1.09) 0.50 1.03 (0.89, 1.20) 0.67
IgM:     
MSP3 0.62 (0.49, 0.80) < 0.0001 0.76 (0.59, 0.97) 0.03
MSP1 0.59 (0.47, 0.75) < 0.0001 0.68 (0.53, 0.88) < 0.01
GLURP 0.71 (0.58, 0.87) < 0.01 0.84 (0.68, 1.03) 0.09
AMA1 0.48 (0.34, 0.67) < 0.0001 0.63 (0.44, 0.91) 0.01
  1. Malaria incidence rate ratios (IRR) with 95% confidence interval, corresponding to a doubling of baseline antibody level, before and after adjustment for the effect of age.