|
Antigen
|
Antibody
|
Crude IRR (95%CI)
|
P-value
|
Age-adjusted IRR
|
P-value
|
|---|
|
MSP3
| | | | | | |
| |
IgG2*
|
(coded as log(2))
|
0.74 (0.57, 0.98)
|
0.04
|
0.85 (0.63, 1.15)
|
0.29
|
| |
IgG4
|
< detection limit
|
1
|
0.01
|
1
|
0.20
|
| | |
< median
|
0.45 (0.21, 0.95)
| |
0.56 (0.26, 1.19)
| |
| | |
≥ median
|
0.47 (0.28, 0.79)
| |
0.68 (0.40, 1.15)
| |
|
MSP1
19
| | | | | | |
| |
IgG2*
|
(coded as log(2))
|
0.62 (0.45, 0.86)
|
< 0.01
|
0.836 (0.606, 1.157)
|
0.275
|
| |
IgG4*
|
(coded as log(2))
|
1.07 (0.95, 1.21)
|
0.25
|
0.838 (0.608, 1.159)
|
0.278
|
|
GLURP
| | | | | | |
| |
IgG2*
|
(coded as log(2))
|
0.65 (0.49, 0.86)
|
< 0.01
|
0.79 (0.58, 1.08)
|
0.13
|
| |
IgG4*
|
(coded as log(2))
|
0.94 (0.81, 1.08)
|
0.37
|
1.01 (0.87, 1.16)
|
0.94
|
|
AMA1
| | | | | | |
| |
IgG2
|
< detection limit
|
1
|
0.18
|
1
|
0.54
|
| | |
< median
|
1.80 (0.86, 3.78)
| | | |
| | |
≥ median
|
1.78 (0.90, 3.51)
| | | |
| |
IgG4
|
< detection limit
|
1
|
0.19
|
1
|
0.54
|
| | |
< median
|
0.96 (0.47, 1.93)
| | | |
| | |
≥ median
|
0.62 (0.36, 1.07)
| | | |
- For IgG 2 to AMA1 and for IgG4 to AMA1 and MSP3, antibody level was categorized.
- *For IgG2 to MSP3, MSP119 and GLURP, the association is expressed as the incidence rate ratio (IRR) corresponding to a doubling of baseline antibody level.
