Antigen

Antibody

Crude IRR (95%CI)

Pvalue

Ageadjusted IRR

Pvalue


MSP3
      

IgG2*

(coded as log(2))

0.74 (0.57, 0.98)

0.04

0.85 (0.63, 1.15)

0.29


IgG4

< detection limit

1

0.01

1

0.20

 
< median

0.45 (0.21, 0.95)
 
0.56 (0.26, 1.19)
 
 
≥ median

0.47 (0.28, 0.79)
 
0.68 (0.40, 1.15)
 
MSP1
_{19}
      

IgG2*

(coded as log(2))

0.62 (0.45, 0.86)

< 0.01

0.836 (0.606, 1.157)

0.275


IgG4*

(coded as log(2))

1.07 (0.95, 1.21)

0.25

0.838 (0.608, 1.159)

0.278

GLURP
      

IgG2*

(coded as log(2))

0.65 (0.49, 0.86)

< 0.01

0.79 (0.58, 1.08)

0.13


IgG4*

(coded as log(2))

0.94 (0.81, 1.08)

0.37

1.01 (0.87, 1.16)

0.94

AMA1
      

IgG2

< detection limit

1

0.18

1

0.54

 
< median

1.80 (0.86, 3.78)
   
 
≥ median

1.78 (0.90, 3.51)
   

IgG4

< detection limit

1

0.19

1

0.54

 
< median

0.96 (0.47, 1.93)
   
 
≥ median

0.62 (0.36, 1.07)
   
 For IgG 2 to AMA1 and for IgG4 to AMA1 and MSP3, antibody level was categorized.
 *For IgG2 to MSP3, MSP1_{19} and GLURP, the association is expressed as the incidence rate ratio (IRR) corresponding to a doubling of baseline antibody level.