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Table 4 Association of IgG1 and IgG3 with malaria incidence

From: Cohort study of the association of antibody levels to AMA1, MSP119, MSP3 and GLURP with protection from clinical malaria in Ghanaian children

IgG1: Crude IRR (95%CI) P-value IRR adjusted for age (95%CI) P-value
   MSP3 0.82 (0.72, 0.94) < 0.01 0.88 (0.76, 1.03) 0.11
   MSP119 0.86 (0.77, 0.97) 0.01 0.89 (0.80, 0.99) 0.04
   GLURP 0.85 (0.74, 0.98) 0.02 0.93 (0.81, 1.08) 0.35
   AMA1 0.95 (0.86, 1.06) 0.36 1.01 (0.90, 1.14) 0.83
IgG3:     
   MSP3 0.90 (0.82, 0.98) 0.01 0.94 (0.86, 1.03) 0.17
   MSP119 0.90 (0.82, 0.99) 0.03 0.93 (0.84, 1.03) 0.18
   GLURP 0.83 (0.74, 0.93) < 0.01 0.91 (0.80,1.03) 0.14
   AMA1 0.97 (0.89, 1.06) 0.48 0.98 (0.90, 1.07) 0.73
  1. The incidence rate ratio (IRR) corresponds to a doubling of baseline antibody level, before and after adjustment for effects of age