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Table 4 Prevalence and levels of antibodies to the OR domain of the P. falciparum P126 protein in Candeias do Jamari and Peixoto de Azevedo groups according to the infection patterns.

From: Evaluation of the genetic polymorphism of Plasmodium falciparum P126 protein (SERA or SERP) and its influence on naturally acquired specific antibody responses in malaria-infected individuals living in the Brazilian Amazon

Infection

IgG

IgM

IgG1

IgG2

IgG3

IgG4

 

Candeias do Jamari (CJ)

OR-II

      

   CJ-1993

47/69 (68)

4.9 ± 3.0d

39/63 (62)

3.4 ± 2.1

39/44a(88)

3.2 ± 2.1e

6/44b(13)

3.1 ± 2.9

42/44c(95)

10.6 ± 10.0

19/44 (43)

1.6 ± 0.7f

   CJ-2002

55/70 (78)

8.4 ± 8.2j

57/70g (81)

4.8 ± 4.8

13/55h (23)

1.9 ± 0.7

19/55i(34)

1.3 ± 0.4

35/55 (60)

7.5 ± 6.1

23/55 (42)

2.6 ± 2.2k

 

Peixoto de Azevedo (PA)

OR-I

19/25 (76)

4.9 ± 2.9

13/25 (52)

1.7 ± 0.9

13/18l (72)

2.0 ± 1.8

0/18m

-

18/18n (100)

9.8 ± 6.8

9/18 (50)

1.4 ± 0.2

OR-II

36/46 (78)

4.3 ± 2.7

27/46 (59)

2.7 ± 1.7

21/36o (58)

2.1 ± 1.7

5/36p (14)

1.3 ± 0.4

34/36q (94)

7.6 ± 6.1

16/36 (44)

1.3 ± 0.1

Mixed

16/19 (84)

4.5 ± 3.1

9/19 (47)

2.0 ± 1.4

11/16r(69)

2.9 ± 2.7

0/16s

-

16/16 (100)t

7.5 ± 6.4

5/16 (31)

1.3 ± 0.1

  1. The data represent the number of responders/total of each fragment tested (the percentage of responders is given in parentheses) and the antibody levels expressed as mean of OD index ± SD. P < 0.05. a: CJ-1993- IgG1 > IgG2, IgG1 > IgG4; CJ-1993 IgG1 > CJ-2002 IgG1; b: CJ-1993- IgG2 < IgG3, IgG2 < IgG4; CJ-1993 IgG2 < CJ-2002 IgG2; c: CJ-1993- IgG3 > IgG4; CJ-1993 IgG3 > CJ-2002 IgG3; d: CJ-1993 IgG < CJ-2002 IgG; e: CJ-1993 IgG1 > CJ-2002 IgG1; f: CJ-1993 IgG4 < CJ-2002 IgG4; g: CJ-2002 IgM > CJ-1993 IgM, CJ-2002 IgM > PA IgM; h: CJ-2002 IgG1 < IgG3; i: CJ-2002 IgG2 < IgG3; CJ-2002 IgG2 > PA OR-II IgG2; j: CJ-2002 IgG > PA OR-II IgG; k: CJ-2002 IgG4 > PA OR-II IgG4 l: PA OR-I IgG1 > IgG2; PA OR-I IgG1 < IgG3; m: PA OR-I IgG2 < IgG3; PA OR-I IgG2 < IgG4; n: PA OR-I IgG3 > IgG4; o: PA OR-II IgG1 > IgG2; PA OR-II IgG1 < IgG3; p: PA OR-II IgG2 < IgG3; PA OR-II IgG2 < IgG4; q: PA OR-II IgG3 > IgG4; CJ-2002 IgG3 < PA OR-II IgG3; r: PA mixed IgG1 > IgG2; s: PA mixed IgG2 > IgG3; t: PA mixed IgG3 > IgG4. The Student's t-test was used to analyse the differences in mean values, the Chi-square test was used to analyse the difference in prevalence of positive responses.