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Table 3 Day 28 failure rates estimated by four methods – AL treatment

From: Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children

  

Day 28 failure rates

% [CI95%]

  

Method 1a

(per protocol)

Method 1b

Method 2a

(WHO 2001)

Method 2b

2004

Angola, Caala

0

0

0

0

  

[0–6.1]*

[0–6.0]*

  

2004

Congo, Kindamba

1.2

1.1

1.1

1.0

  

[0–6.2]

[0–6.0]

[0.2–7.3]

[0.1–6.8]

2005

Burkina Faso, Bobo-Dioulasso

3.2

2.8

2.8

2.8

  

[0.9–8.1]

[0.8–6.9]

[1.1–7.3]

[1.1–7.3]

2005

Uganda, Tororo

3.3

1.6

1.8

1.8

  

[0.7–9.3]

[0.3–4.7]

[0.6–5.4]

[0.6–5.7]

  1. *one-sided 97.5% Cis