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Table 3 Changes in the percentage of patients presenting symptoms of malaria attack during the study

From: Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the treatment of uncomplicated falciparum malaria

Symptoms Percentage of patients with symptoms on D0 Percentage of patients with symptoms on D3 Percentage of patients with symptoms on D14
One intake N = 161 Two intakes N = 155 One intake N = 161 Two intakes N = 155 One intake N = 161 Two intakes N = 155
Headache 88.8% 91.0% 5.0% 1.9% 0.6% 0.7%
Perspiration 59.0% 55.5% 10.6% 9.7% 1.2% 3.9%
Dizziness 42.2% 45.2% 8.7% 7.1% 0.6% 1.3%
Chills 69.6% 67.7% 3.1% 4.5% 0.6% 2.6%
Pain 41.6% 40.6% 5.7% 10.3% 1.9% 2.6%
Anorexia 70.8% 71.6% 19.8% 15.5% 1.2% 0
Asthenia 77.0% 74.8% 39.1% 38.7% 0.6% 0.6%
Jaundice 1.9% 0.6% 0.6% 0 0 0
Skinfold 0.6% 0.6% 1.3% 1.3% 0 0
Hepatomegaly 7.5% 5.8% 7.5% 3.9% 5.8% 3.9%
Vomiting in 24 hours 47.8% 43.9% 3.7% 2.5% 0 0
Diarrhoea in 24 hours 9.3% 8.4% 1.8% 2.5% 0 1.3%