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Table 4 Biochemical Characteristics of Patients on Day 0, 7 and 28

From: Efficacy, safety and tolerability of artesunate-mefloquine in the treatment of uncomplicated Plasmodium falciparum malaria in four geographic zones of Nigeria

 

Treatment Group 1 (> 30 kg)

Treatment Group 2 (15–29 kg)

D0

D7

D28

D0

D7

D28

Alkaline Phosphatase (iu/L)

159.55 ± 121.58

156.95 ± 92.51

145.66 ± 99.40

220.64 ± 85.33

181.96 ± 69.98

197.12 ± 86.01

Aspartate amino Transferase (iu/L)

29.12 ± 19.54

21.96 ± 14.54

21.31 ± 16.15

38.58 ± 42.55

21.26 ± 14.21

24.47 ± 21.16

Alanine amino Transferase (iu/L)

20.41 ± 24.94

12.24 ± 10.0

14.23 ± 18.66

23.04 ± 20.40

10.64 ± 9.06

13.17 ± 9.99

Total biribin (μmoi/L)

6.16 ± 6.35

2.80 ± 4.61

4.53 ± 4.42

5.12 ± 5.63

0.95 ± 2.25

4.03 ± 3.59

Conjugated bilirubin (μmoi/L)

2.75 ± 3.25

0.29 ± 0.16

0.27 ± 0.19

0.49 ± 0.58

0.31 ± 0.16

0.38 ± 0.32

Urea

8.96 ± 7.14

8.58 ± 8.90

8.06 ± 8.02

8.22 ± 5.95

8.06 ± 7.43

8.43 ± 7.88

Creatinine

34.12 ± 31.81

38.12 ± 30.55

33.06 ± 91.10

21.97 ± 21.78

24.73 ± 20.92

22.16 ± 20.25