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Table 2 Comparison of αMSP1-19kD IgG responses with malaria infection status during community surveys.

From: Antibody response dynamics to the Plasmodium falciparum conserved vaccine candidate antigen, merozoite surface protein-1 C-terminal 19kD (MSP1-19kD), in Peruvians exposed to hypoendemic malaria transmission

Malaria status Age group N (n < neg cut-off, n > 3* neg cut-off) Median Lower quartile Upper quartile p (WRS test)
PF Adults 14 (1, 14) 1.446 1.141 1.851 0.3132
PF Children 14 (3, 8) 1.339 0.740 1.803  
NEG Adults 433 (141, 227) 1.040 0.505 1.562 <0.0001
NEG Children 435 (302, 89) 0.301 0.161 0.827  
  1. In adults, P. falciparum infected, P. vivax infected, and Plasmodium-negative (NEG) individuals had similar αMSP1-19kD IgG OD levels. The low αMSP1-19kD response frequency in NEG children suggests that fewer children had prior P. falciparum infection which could explain the maintained αMSP1-19kD antibody response seen in adults.