Table 2 Results of the levels of different antibodies isotypes and their avidity against P. falciparum blood stages determined by ELISA in serum from 233 individuals infected with Plasmodium and classified according to the different clinical expressions of malaria: complicated malaria (CM), uncomplicated malaria (UM) and asymptomatic malaria (AS).

IgG1*

2.28 (0.80–10.37)

18.40 (7.23–44.8)

38.4 (3.95–71.8)

< 0.0001

AI-IgG1+

35.1 (24.7–64.7)

66.4 (44.4–86.7)

71.9 (62.2–84.6)

< 0.0001

IgG2*

1.33 (0.67–3.00)

3.92 (2.26–17.1)

9.81 (2.25–89.8)

< 0.0001

AI-IgG2+

20.4 (16.8–68.6)

58.0 (37.5–76.6)

75.3 (62.0–92.6)

0.014

IgG3*

0.43 (0.19–0.91)

1.53 (0.72–3.74)

2.41 (0.53–9.47)

< 0.0001

AI-IgG3+

43.5 (22.0–53.6)

42.9 (27.1–66.5)

37.1 (29.4–53.3)

0.813

IgG4*

0.06 (0.00–0.14)

0.01 (0.00–0.04)

0.01 (0.00–0.03)

0.002

AI-IgG4+

40.0 (2.8–77.8)

48.9 (36.0–59.1)

-

0.471

IgG#

2.47 (0.73–5.44)

2.92 (1.36–4.39)

4.71 (1.59–6.58)

0.190

AI-IgG+

48.4 (34.7–69.7)

63.3 (46.8–73.2)

63.4 (58.2–69.8)

0.036

IgE*

0.07 (0.03–0.16)

0.03 (0.00–0.11)

0.03 (0.01–0.21)

0.07

IgM#

1.08 (0.65–2.08)

0.86 (0.59–1.50)

1.04 (0.58–2.00)

0.106

IgA#

0.93 (0.56–2.09)

0.87 (0.60–1.88)

-

0.661